FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to medicine, biology, nanothechnology, and deals with obtaining immunogenic compositions. Claimed immunogenic composition contains 1) platform-carrier, for which used are spherical particles, obtained by thermal structural restructuring of viruses belonging to group of tobacco mosaic virus (tobamoviruses) or other plant viruses with spiral structure and 2) foreign proteins/antigens/epitopes, bound with surface of spherical particles. Foreign antigen/epitope in composition of complex with spherical particles demonstrates high immunogenicity and preserves antigenic specificity.
EFFECT: claimed compositions are biologically safe, stable.
10 ex, 13 dwg
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Authors
Dates
2012-01-20—Published
2010-12-09—Filed