FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry and specifically to a method of producing N-nitromethyl azoles of formula 
where R= 
, 
, 
, 
, 
, which can be used as biologically active substances and intermediates during synthesis of other azole derivatives. The method of producing N-nitromethyl azole derivatives is realised by treating a ketone with a corresponding azole acetic acid and nitric acid mixture at 50-60°C in the presence of 0.05-0.25 mole sodium nitrite per mole of the initial ketone. The volume ratio of nitric acid (58-70% concentration) to glacial acetic acid is equal to 1:6.
EFFECT: novel method of producing N-nitromethyl azole derivatives and synthesis of novel N-nitromethyl derivatives of 3-nitro-1,2,4-triazole.
1 cl, 5 ex
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