METHOD FOR SELECTION AND OBTAINING OF HIGHLY SELECTIVE AND MULTISPECIFIC TARGETING GROUPS WITH SPECIFIED PROPERTIES, INCLUDING AT LEAST TWO DIFFERENT BINDING GROUPS, AND THEIR APPLICATIONS Russian patent published in 2017 - IPC C07K16/00 C07K16/46 C12N9/16 C12P21/00

Abstract RU 2639287 C2

FIELD: biotechnology.

SUBSTANCE: method for determination of an antigen-binding sites combination is disclosed.

EFFECT: invention allows to obtain bispecific antibodies.

2 cl, 2 tbl, 4 ex

Similar patents RU2639287C2

Title	Year	Author	Number
METHOD FOR PRODUCTION AND SELECTION OF MOLECULES INCLUDING, AT LEAST TWO DIFFERENT GROUPS, AND APPLICATION THEREOF	2013	Bek Maril Tifentaler Georg	RU2646159C2
HUMANISED HUMAN CD19 ANTIBODIES AND METHODS FOR USE THEREOF	2016	Zhorzh Gi Messner Ekkekhard Lariver Loran Khaas Aleksandr Kettenberger Gubert Ferrara Koller Klaudia Shlotauer Tilman Molkhoj Mikhel	RU2731156C1
ANTIBODIES AGAINST TRANSFERRIN RECEPTOR HAVING INDIVIDUALIZED AFFINITY	2016	Dengl, Stefan Zhorzh, Gi Gepfert, Ulrikh Nivener, Jens Shlotauer, Tilman	RU2729416C2
METHOD FOR DETECTING ANTIBODIES TO DRUGS WITH RESPECT TO HUMAN OR HUMANISED MEDICINAL ANTIBODIES WITH SUPPRESSED EFFECTOR FUNCTION	2015	Umana Pablo Vessels Uve Shtubenraukh Kaj-Gunnar	RU2719642C2
COVALENTLY LINKED CONJUGATES CHELICAR-ANTIBODY AGAINST CHELICAR AND USE THEREOF	2014	Brinkmann Ulrikh Georges Gaj Khoffmann Ajke Tifentaler Georg Messner Ekkekhard Dengl Stefan Gertner Akhim	RU2694981C2
BISPECIFIC ANTI-HAPTEN/ANTI-BLOOD BRAIN BARRIER RECEPTOR ANTIBODIES, COMPLEXES THEREOF AND THEIR USE AS BLOOD BRAIN BARRIER SHUTTLES	2014	Brinkmann Ulrikh Georges Gaj Mundigl Olaf Nivener Ens	RU2693438C2
EMBODIMENTS OF Fc-REGION WITH MODIFIED BINDING PROPERTIES OF FcRn AND PROTEIN A	2015	Shlotauer Tilman	RU2713131C1
METHOD OF SELECTING ANTIBODIES WITH MODIFIED INTERACTION WITH FcRn	2015	Foged Ensen Pernille Kettenberger Gubert Kenig Maksimilian Rand Kasper Shlotauer Tilman	RU2714153C2
ANTIBODIES TO BIOTIN AND APPLICATION METHODS	2013	Brinkmann Ulrikh Zhorzh Gi Grote Majkl Khoffmann Ajke	RU2630296C2
VARIANTS OF Fc-DOMAIN WITH MODIFIED FcRn BINDING AND METHODS OF APPLICATION THEREOF	2015	Messner Ekkekhard Shlotauer Tilman	RU2714116C2

RU 2 639 287 C2

Authors

Fenn Sebastyan

Kopetski Erkhard

Tifentaler Georg

Dates

2017-12-20—Published

2013-06-25—Filed