BIOTRANSPLANT FOR CORRECTION OF SOFT TISSUE DEFECTS (VERSIONS), METHOD OF BIOTRANSPLANT OBTAINING (VERSIONS) AND METHOD OF CORRECTION OF SOFT TISSUE DEFECTS Russian patent published in 2011 - IPC A61K35/36 A61Q19/08 C12N5/73 

FIELD: medicine.

SUBSTANCE: invention represents biotransplant for correction of soft tissue defects, characterised by the fact that it represents suspension which contains autologic culture of fibroblasts in 0.9% solution of sodium chloride in concentration 0.6-3.0×10⁶ in 1 ml of biotransplant, integrated on pharmaceutically acceptable biocompatible biodegradable crushed to size of 100-200 mcm cell-free matrix in solution of pharmaceutically acceptable biocompatible biodegradable preparation of hyaluronic acid, volume ratio of autologic culture of fibroblasts, cell-free matrix and preparation of hyaluronic acid constitutes 4:1:1 respectively, and as pharmaceutically acceptable biocompatible biodegradable cell-free matrix used is preparation "Saimetra", representing processed donor human skin, deprived of cells and structural immunospecific proteins, whose basis consists of collagen and elastin, represented as injection form.

EFFECT: considerable reduction of quantity of injected cells, increase of their viability and ensuring long preservation of implant in affected tissue.

19 cl, 4 ex, 5 dwg