FIELD: chemistry.
SUBSTANCE: described is a method of producing chitosan-based films, involving preparation of a moulding solution from an air-dried weighed portion of chitosan and a solution of organic acid, depositing the obtained solution onto a substrate and then holding the solution on the substrate until obtaining a film structure, wherein the moulding solution contains chitosan in form a salt of acetic or amber acid. After holding, the film structure is treated water vapour or vapour of 0.5 N hydrochloric acid solution until achieving film swelling index of 70-190%. The elongation at rupture of the film is not less than 20%. Described also is a method in which the film is put into distilled water or a physiological solution (0.9% NaCl) until achieving film swelling index of not less than 90%. The elongation at rupture of the film is not less than 30%.
EFFECT: highly elastic, non-toxic, biocompatible and biodegradable film made from chitosan, having curative effect when healing various wounds, during mechanical or thermal tissue injury in animals or humans.
2 cl, 10 tbl, 77 ex
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Authors
Dates
2011-09-20—Published
2010-07-16—Filed