METHOD OF TREATING OROPHARYNGEAL SQUAMOUS CELL CARCINOMA Russian patent published in 2011 - IPC A61N5/00 A61K31/282 A61K39/395 A61P35/00 

FIELD: medicine.

SUBSTANCE: treatment of oropharyngeal squamous cell carcinoma is ensured by drop-by-drop introduction of cetuximab 400 mg/m² for the first day of the first week. Then from the first day of the second week, radiation therapy of large fractions 4 Gy is combined with introduction of cisplatin 30 mg for 3 days running. On the first day of the second to the fifth week, cetuximab 250 mg/m² is introduced drop-by-drop. Further, a dose of radiation therapy is 2 Gy once a day, 5 times a week to total basic dose 30-40 Gy. In 2 weeks, the course is performed again to total basic dose 70 Gy according to the same scheme.

EFFECT: method allows increasing rate and degree of primary tumour regress, suppressing sub-clinical disseminated metastases, ensuring maximum anticancer effect without injuring normal tissue cells, enables preserving organ functions, increasing a number of organ-saving surgeries, improving quality of life of the patients, reducing invalidisation.

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