FIELD: chemistry.
SUBSTANCE: invention relates to novel 5-(4-hydroxyphenyl)-4-(4-methoxybenzoyl)-3-hydroxy-1-(2,2-dimethoxyethyl)-3-pyrrolin-2-one of formula 
. LD50 during intraperitoneal administration to white mice is equal to 3250 (1716-5020) mg/kg.
EFFECT: compound has analgesic and antipyretic properties.
2 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| ANALGESIC AGENTS BASED ON 5-ARYL-4-BENZOYL-3-HYDROXY-1-(4-GUANIDYLSULFONYLPHENYL)-3-PYRROLIN-2-ONES | 2016 |
|
RU2644161C2 |
| USE OF 5-ARYL-4-AROYL-3-HYDROXY-1-CARBOXYMETHYL-3-PYRROLIN-2-ONES AS ANALGESICS | 2023 |
|
RU2816900C1 |
| USE OF 4-[1-(4-METHYLPHENYL)AMINOETHYLIDENE]-5-PHENYL-1-CYANOMETHYLTETRAHYDROPYRROLE-2,3-DIONE AS AN ANALGESIC | 2023 |
|
RU2806330C1 |
| METHYL 4-HYDROXY-4-METHYL-6-PHENYL-2-CYANOACETYLHYDRAZONOCYCLOHEXANE-1-CARBOXYLATE EXHIBITING ANALGESIC ACTIVITY | 2010 |
|
RU2446150C2 |
| USE OF 5-BENZOYL-4-HYDROXY-N-(4-IODOPHENYL)-6-(4-CHLOROPHENYL)-2-OXOHEXAHYDROPYRIMIDINE-4-CARBOXAMIDE AS AGENT WITH ANALGESIC ACTIVITY | 2023 |
|
RU2811249C1 |
| USE OF METHYL 5-BENZOYL-4-HYDROXY-6-(4-CHLOROPHENYL)-2-THIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLATE AS AN AGENT HAVING ANALGESIC AND ANTI-INFLAMMATORY ACTION | 2024 |
|
RU2835600C1 |
| ETHYL 4-(5-BENZOYL-6-(4-(DIETHYLAMINO)PHENYL)-4-HYDROXY-2-THIOXOHEXAHYDROPYRIMIDIN-4-CARBOXAMINO)BENZOATE, EXHIBITING ANALGESIC AND ANTI-INFLAMMATORY ACTION | 2019 |
|
RU2717246C1 |
| USE OF 4-(4-BROMOPHENYL)-6-METHYL-2-THIOXO-N-(O-TOLYL)-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXAMIDE AS AGENT HAVING ANALGESIC ACTIVITY | 2024 |
|
RU2835601C1 |
| 4-METHYL-N-2,4-DIMETHYLPHENYL-6-(3-FLUOROPHENYL)-2-THYOXO-1,2,3,6-TETRAGYDROPYRIMIDINE-5-CARBOXAMIDE THAT HAS ANALGETIC ACTION | 2015 |
|
RU2653511C2 |
| USE OF 4-(4-BROMOPHENYL)-6-METHYL-N-(2-CHLOROPHENYL)-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXAMIDE AS AN AGENT WITH ANALGESIC ACTIVITY | 2022 |
|
RU2793550C1 |
