FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry, pyrimidine derivatives, specifically to ethyl 4-(5-benzoyl-6-(4-(diethylamino)phenyl)-4-hydroxy-2-thioxohexahydropyrimidin-4-carboxamino)benzoate (1) of formula:
.
EFFECT: disclosed compound exhibits analgesic and anti-inflammatory action, which enables to use it as an analgesic and anti-inflammatory agent.
1 cl, 3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| USE OF 5-BENZOYL-4-HYDROXY-N-(4-IODOPHENYL)-6-(4-CHLOROPHENYL)-2-OXOHEXAHYDROPYRIMIDINE-4-CARBOXAMIDE AS AGENT WITH ANALGESIC ACTIVITY | 2023 |
|
RU2811249C1 |
| USE OF 4-[1-(4-METHYLPHENYL)AMINOETHYLIDENE]-5-PHENYL-1-CYANOMETHYLTETRAHYDROPYRROLE-2,3-DIONE AS AN ANALGESIC | 2023 |
|
RU2806330C1 |
| 5-(4-HYDROXYPHENYL)-4-(4-METHOXYBENZOYL)-3-HYDROXY-1-(2,2-DIMETHOXYETHYL)-3-PYRROLIN-2-ONE, EXHIBITING ANALGESIC AND ANTIPYRETIC PROPERTIES | 2009 |
|
RU2429229C1 |
| ANALGESIC AGENTS BASED ON 5-ARYL-4-BENZOYL-3-HYDROXY-1-(4-GUANIDYLSULFONYLPHENYL)-3-PYRROLIN-2-ONES | 2016 |
|
RU2644161C2 |
| USE OF 1,6-(4-BROMOPHENYL)-4-METHYL-N-(2-CHLOROPHENYL)-1,2,3,4-THIOXO-5-TETRAHYDROPYRIMIDINE-5-CARBOXAMIDE AS AN AGENT WITH ANALGESIC ACTIVITY | 2022 |
|
RU2796070C1 |
| METHYL 4-HYDROXY-4-METHYL-6-PHENYL-2-CYANOACETYLHYDRAZONOCYCLOHEXANE-1-CARBOXYLATE EXHIBITING ANALGESIC ACTIVITY | 2010 |
|
RU2446150C2 |
| USE OF 5-ARYL-4-AROYL-3-HYDROXY-1-CARBOXYMETHYL-3-PYRROLIN-2-ONES AS ANALGESICS | 2023 |
|
RU2816900C1 |
| USE OF 4-(4-BROMOPHENYL)-6-METHYL-N-(2-CHLOROPHENYL)-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXAMIDE AS AN AGENT WITH ANALGESIC ACTIVITY | 2022 |
|
RU2793550C1 |
| 1-HEXADECYL-4,6-DIMETHYL-2-OXONICOTINAMIDE EXHIBITING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | 2008 |
|
RU2396258C2 |
| N-(4'-METHYLBENZOYL)-3,5-DICHLOROANTHRANILIC ACID BUTYLAMIDE EXHIBITING ANTI-INFLAMMATORY AND ANALGETIC ACTIVITY | 2020 |
|
RU2753655C1 |
