FIELD: organic chemistry.
SUBSTANCE: invention relates to the use of biologically active compounds of the class N,4-diaryl-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamides, namely 4-(4-bromophenyl)-6-methyl-N-(2-chlorophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide. The invention relates to the use of 4-(4-bromophenyl)-6-methyl-N-(2-chlorophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide of the following formula (1):
1
as an agent with analgesic activity.
EFFECT: proposed compound has a higher analgesic activity with low toxicity, which makes it possible to use it to create a new drug with analgesic activity.
1 cl, 2 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
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|
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|
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|
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|
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RU2806330C1 |
| APPLICATION OF METHYL 5-BENZOYL-6-(4-FLUOROPHENYL)-4-METHOXY-2-THIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLATE AS AN ANTI-INFLAMMATORY AGENT | 2022 |
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RU2786805C1 |
| USE OF 5-ARYL-4-AROYL-3-HYDROXY-1-CARBOXYMETHYL-3-PYRROLIN-2-ONES AS ANALGESICS | 2023 |
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RU2816900C1 |
| 5-(4-HYDROXYPHENYL)-4-(4-METHOXYBENZOYL)-3-HYDROXY-1-(2,2-DIMETHOXYETHYL)-3-PYRROLIN-2-ONE, EXHIBITING ANALGESIC AND ANTIPYRETIC PROPERTIES | 2009 |
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| ANALGESIC AGENTS BASED ON 5-ARYL-4-BENZOYL-3-HYDROXY-1-(4-GUANIDYLSULFONYLPHENYL)-3-PYRROLIN-2-ONES | 2016 |
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RU2644161C2 |
