NOVEL CRYSTALS OF 3-[5-[4-(CYCLOPENTYLOXY)-2-HYDROXYBENZOYL]-2-[(3-HYDROXY-1,2-BENZISOXAZOL-6-YL) METHOXY]PHENYL]PROPIONIC ACID Russian patent published in 2011 - IPC C07D261/12 A61K31/42 

Abstract RU 2429233 C2

FIELD: chemistry.

SUBSTANCE: invention relates to crystals of 3-{5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-hydroxy-1,2-benzisoxazol-6-yl)methoxy]phenyl}-propionic acid. The crystals are characterised by peaks at positions 14.0, 16.0, 23.3, 23.7 and 26.3° (form II) and at positions 14.6, 23.1, 24.7, 25.6 and 26.0° (form III) at diffraction angle 2θ on an X-ray powder pattern.

EFFECT: said propionic acid compounds have low specific volume, are not well charged with electricity and can be used as an active pharmaceutical ingredient of antirheumatic medicinal agents.

2 cl, 3 dwg, 4 tbl, 7 ex

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RU 2 429 233 C2

Authors

Jonezava Kendzi

Kotsubo Khironori

Baba Jasutaka

Tada Jukie

Dates

2011-09-20Published

2007-05-25Filed