FIELD: medicine.
SUBSTANCE: method for producing EHF Diagnosticum by reproduction of four hantaviruses - Puumala strain PUU-TDK/VERO, Dobrava strain DOB-EAT-VERO, Hantaan strain Ussuri-4590 and Seoul strain SK-515/Georgia-88, in a monolayer passaged cell culture of VERO-line grass monkey kidneys, followed by virus-specific antigen concentration test, polyvalent antigen production, antigen fixation on a slide and UV processing.
EFFECT: invention provides a more sensitive diagnostic test, presenting a low-price production process and more effective use of the EHF Diagnosticum.
4 cl, 2 ex, 1 tbl
Title | Year | Author | Number |
---|---|---|---|
HEMORRHAGIC FEVER AND RENAL SYNDROME CAUSAL VIRUS STRAIN FOR PREPARING VACCINE PREPARATIONS (VERSIONS) | 2009 |
|
RU2423520C1 |
METHOD FOR PREPARING COMBINED BIVALENT, TISSUE-CULTURE, INACTIVATED, CONCENTRATED, PURIFIED VACCINE FOR PREVENTING HEMORRHAGIC FEVER AND RENAL SYNDROME | 2009 |
|
RU2445117C2 |
METHOD FOR PRODUCING "HANTA-N" TEST SYSTEM FOR DETERMINING SPECIFIC ACTIVITY OF VACCINE AGAINST HEMORRHAGIC FEVER WITH RENAL SYNDROME | 2012 |
|
RU2590606C2 |
VIRUS STRAIN FOR PRODUCING VACCINE DRUGS AGAINST HEMORRHAGIC FEVER WITH RENAL SYNDROME (OPTIONS) | 2018 |
|
RU2683508C1 |
METHOD OF OBTAINING IMMUNOENZYMATIC TEST SYSTEM FOR DETERMINATION OF EPITOPES OF ENVELOPE PROTEIN OF PUUMALA VIRUS WITH PROTECTIVE ORIENTATION IN VACCINE PREPARATIONS AGAINST HAEMORRHAGIC FEVER WITH RENAL SYNDROME | 2013 |
|
RU2565543C2 |
METHOD OF PRODUCTION OF RECOMBINANT ANTIGEN G2 OF HANTAVIRUS DOBRAVA IN CELLS OF E coli | 2011 |
|
RU2495938C2 |
METHOD OF CHANTA-VIRUS DIAGNOSTICUM PREPARING | 2000 |
|
RU2180754C2 |
STRAIN OF VIRUS OF HEMORRHAGIC FEVER WITH RHENAL SYNDROME, USED FOR SPECIFIC LABORATORY DIAGNOSIS | 0 |
|
SU1319555A1 |
METHOD OF OBTAINING RECOMBINANT ANTIGEN G2 OF DOBRAVA HANTAVIRUS IN E.coli CELLS | 2012 |
|
RU2509805C2 |
STRAIN OF VIRUS OF HEMORRHAGIC FEVER WITH KIDNEY SYNDROME OF 2ND SEROTYPE FOR SPECIFIC LABORATORY DIAGNOSTICS | 0 |
|
SU1319554A1 |
Authors
Dates
2011-10-10—Published
2010-05-05—Filed