FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology. Described is method for producing immuno-enzyme test system for estimation of content of immune-specific proteins of hanta-viruses as Puumala, Dobrava, Hantaan, and Seoul in vaccine preparations against hemorrhagic fever with renal syndrome (HFRS).
EFFECT: method implies production of monoclonal antibodies to Puumala and Dobrava viruses with similar sensitivity, in accordance with virus titre, for detecting antigens of each of four hanta-viruses which cause HFRS, and their subsequent sorption upon surface of polystyrene panel.
1 cl, 3 tbl, 2 ex
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|---|---|---|---|
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| pET21-GST-CD RECOMBINANT PLASMID WHICH ENSURES SYNTHESIS AND SECRETION OF Gn ECTODOMAIN OF HANTAAN VIRUS GLYCOPROTEIN, AND BL21(DE3)PLYSE pET21-GST-CD RECOMBINANT ESCHERICHIA COLI STRAIN, PRODUCER OF Gn PROTEIN, ECTODOMAIN OF HANTAAN VIRUS GLYCOPROTEIN | 2023 |
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