FIELD: medicine.
SUBSTANCE: blood serum is analysed for the contents of human tissue inhibitor of matrix metalloproteinases (hTIMP-1) by an ELISA technique. If hTIMP-1 ranges within 138 ng/ml to 183 ng/ml, the presence of early subclinical renal irritation in the patients suffering hypertensive disease with normal glomerular filtration rate with the absence of microalbuminuria is stated.
EFFECT: use of the technique allows diagnosing early subclinical renal irritation in the suffering hypertensive disease with normal glomerular filtration rate with the absence of microalbuminuria, use of the technique makes it possible to control clinical effectiveness.
2 tbl, 2 ex
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