FIELD: medicine.
SUBSTANCE: invention relates to a method of assessing the effectiveness of nephroprotective therapy in hypertensive patients with stage C2 chronic kidney disease. The level of biomarkers of proximal tubular damage NGAL and KIM-1 in urine is determined before starting treatment with antihypertensive drugs and during treatment after 6 months. If a decrease in the level of NGAL in the urine after 6 months of treatment is detected by more than 71.3% and a decrease in the level of KIM-1 in the urine after 6 months of treatment by more than 54.5%, nephroprotective therapy is assessed as effective.
EFFECT: invention provides control over the effectiveness of nephroprotective therapy in hypertensive patients with stage C2 chronic kidney disease and has high sensitivity and specificity.
1 cl, 1 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD OF EARLY DIAGNOSTICS OF KIDNEY DAMAGE IN PATIENTS WITH THE INITIAL STAGE OF CHRONIC KIDNEY DISEASE | 2018 |
|
RU2677289C1 |
METHOD FOR DIAGNOSING EARLY CHRONIC RENAL DISEASE IN CHILDREN | 2020 |
|
RU2753581C1 |
EARLY DIAGNOSTIC TECHNIQUE FOR CHRONIC RENAL DISEASE | 2013 |
|
RU2566709C2 |
METHOD FOR EARLY DIAGNOSTICS OF ACUTE RENAL INJURY IN ONCUUROLOGICAL PATIENTS AFTER RADICAL CYSTECTOMY | 2021 |
|
RU2760501C1 |
METHOD FOR PREDICTION OF DEVELOPMENT OF ACUTE KIDNEY DAMAGE DURING MYOCARDIAL INFARCTION IN MEN UNDER 60 YEARS | 2022 |
|
RU2784943C1 |
METHOD FOR EARLY DIAGNOSIS OF CHRONIC TUBULOINTERSTITIAL RENAL INJURY IN PATIENTS WITH ANKYLOSING SPONDYLITIS | 2020 |
|
RU2725850C1 |
METHOD OF EARLY DIAGNOSIS OF ACUTE KIDNEY INJURY-AKI IN PATIENTS WITH ACUTE DECOMPENSATED HEART FAILURE AND CHRONIC KIDNEY DISEASE | 2023 |
|
RU2812203C1 |
DIAGNOSTIC TECHNIQUE FOR STAGES OF CHRONIC KIDNEY DISEASE | 2013 |
|
RU2565394C2 |
METHOD OF DIFFERENTIAL DIAGNOSTICS OF SUBCLINICAL AND STAGES OF CLINICAL ACUTE KIDNEY INJURIES | 2023 |
|
RU2797880C1 |
METHOD FOR DIAGNOSING PRECLINICAL SECONDARY NEPHROPATHIES IN CHILDREN | 2020 |
|
RU2753588C1 |
Authors
Dates
2023-12-27—Published
2023-03-03—Filed