METHOD OF OBTAINING PROANTHOCYANIDIN OLIGOMER Russian patent published in 2011 - IPC A61K31/353 A61K36/00 A61P39/06 A61Q19/08 C07D311/62 

Abstract RU 2435579 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to method of obtaining composition, which has antioxidant activity, containing as main component proanthocyanidin oligomer, which has degree of polymerisation from 2 to 4, which includes stage of heating of proanthocyanidin polymer - containing vegetable materials, or their extract with green tea or its extract or epigallocatechinegallate in water solution of acid and stage of concentration of reaction solution, containing proanthocyanidin oligomer.

EFFECT: claimed method allows to efficiently and easily obtain from vegetable raw material with high output composition of proanthocyanidin oligomer, to whose end position bound is fluoroglycine ring structure and whose molecular weight is reduced to such value, that oligomer can be absorbed in live organism.

8 cl, 17 dwg, 11 ex, 2 ex

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Authors

Tanaka Takashi

Nonaka Gen-Ichiro

Kono Isao

Fudzhi Khadzhime

Nakagava Takashi

Nishioka Khiroshi

Dates

2011-12-10Published

2006-02-24Filed