FIELD: medicine.
SUBSTANCE: there are offered a pharmaceutical composition for treating a overactive bladder (OAB) containing a therapeutically effective amount of a first compound (being an antimuscarinic or anticholinergic agent) and a therapeutically active amount of a second compound (causes salivary gland stimulation), and (i) the first compound is oxybutynin or its acceptable salt, and the second compound is pilocarpin or its salt; or (ii) the first compound is tolterodine or its salt, and the second compound is pilocarpin or its salt, and a relevant method of treating a patient involving introduction of the pharmaceutical composition described above. It is shown that antimuscarinic activity of oxybutynin, responsible for its therapeutic effect on OAB, remains unchanged after introduction of the composition after its adverse side effect - dry mouth - completely neutrolised.
EFFECT: invention leads to more tolerable, effective and profitable treatment.
15 cl, 7 dwg, 3 tbl
Authors
Dates
2011-12-10—Published
2006-08-28—Filed