APPLICATION OF 10-[(3R)-1-AZABICYCLO[2,2,2]OCT-3-YLMETHTYL]-10H-PHENOTHIAZINE FOR PREPARING DRUG SELECTIVELY INHIBITING MUSCARINE RECEPTORS M1L, M2 AND M3 Russian patent published in 2012 - IPC A61K31/5415 A61K9/00 A61P13/10 A61P31/04 A61P31/10 

FIELD: medicine, pharmaceutics.

SUBSTANCE: what is offered is applying 10-[(3R)-1-azabicyclo[2.2.2]oct-3-ylmethyl]-10H-phenothiazine (V0162), as well as its pharmaceutically acceptable salts for preparing a drug applicable for treating or preventing urinary incontinence and related disorders caused by bacterial or mycotic infections developed due to cystic hyperactivity by means of selective inhibition of M₁, M₂- and M₃-muscarine receptors in local and/or oral application.

EFFECT: V0162 decreases intracystic pressure, promotes anticholinergic action in vivo, effectively passes through a mucous membrane, reaching the levels involved in its anticholinergic activity, and when delivered locally has no toxic action neither histologically relation, nor with respect to the vital functions: respiratory rate, pulse, behaviour.

8 cl, 5 tbl, 5 ex