FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to medicine, namely oncology and can be used for treating tumours. What is offered is application of N-hydroxy-3 [4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propenamide (compound of formula III) for preparing a drug intended for the use in a combination with ionising radiation. A system under the invention comprises the compound of formula III in a pharmaceutically acceptable form together with a package leaflet, in a combination with ionising radiation.
EFFECT: use of the inventions allows providing higher clinical effectiveness in solid tumours ensured by synergetic action of the compound of formula III and ionising radiation intensified radiation-induced apoptosis and delayed tumour growth.
4 cl, 7 dwg, 1 ex
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Authors
Dates
2011-12-20—Published
2006-10-23—Filed