FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed is application of inhibitor of hystondeacetylase (HDAL) N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propene amide 
for production of medication for treating myeloma and corresponding method of treatment.
EFFECT: claimed substance demonstrates activity with respect to cell lines of myeloma in very low nanomolecular range, from 50 nM in contrast to earlier known HDAC inhibitors.
7 cl
| Title | Year | Author | Number |
|---|---|---|---|
| HYDROXAMATE DERIVATIVES SUITABLE AS DEACETYLASE INHIBITORS | 2001 |
|
RU2302408C2 |
| COMBINATION OF HISTONE DEACETYLASE INHIBITORS AND RADIATION | 2006 |
|
RU2436572C2 |
| COMBINATION OF HDA INHIBITOR AND ANTIMETABOLITE | 2007 |
|
RU2469717C2 |
| IMIDAZOPYRIMIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | 2014 |
|
RU2691629C1 |
| PYRAZOLOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | 2014 |
|
RU2684641C1 |
| IMIDAZOTHIAZOLE DERIVATIVES AS TNF ACTIVITY MODULATORS | 2014 |
|
RU2683940C1 |
| TRIAZOLOPYRIDAZINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | 2014 |
|
RU2677698C1 |
| IMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | 2014 |
|
RU2696275C1 |
| TETRAHYDROIMIDAZOPYRIDINE DERIVATIVES AS TNF ACTIVITY MODULATORS | 2014 |
|
RU2684635C1 |
| TRIAZOLOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | 2014 |
|
RU2677697C1 |
