IMPROVED OBTAINING OF POLYMERS WITH MOLECULAR IMPRESSIONS Russian patent published in 2011 - IPC A61K31/74 A61K31/78 C08J9/00 B01J20/26 

FIELD: medicine, pharmaceutics.

SUBSTANCE: one aspect of invention relates to improved method of obtaining particles, which consist of polymer with molecular impressions (PMI), which includes enrichment of initially obtained composition, which include insoluble particles of PMI, with PMI particles, binding particular target molecules, thus excluding from initial composition non-binding and low-binding particles. Enrichment is usually carried out by chromatographic methods, acceptable for separation of powder-like material, or by agglutination. Other aspect of invention relates to preparation of improved insoluble PMI by intensified milling of unpurified PMI in order to create a great number of binding centres per weight unit of PMI particles. Preferable aspects of invention include combination of two said aspects.

EFFECT: obtained improved PMI can be applied for diagnostic, analytical and therapeutic purposes, in particular, as per orally introduced medications, which can bind substances, for instance, cholesterol, gall acids and salts of gall acids, present in gastrointestinal tract.

17 cl, 5 dwg, 2 tbl, 6 ex