METHOD OF PHARMACOLOGICAL CORRECTION OF ISCHEMIC TISSUES SURVIVAL RATE IN REDUCED BLOOD CIRCULATION ENVIRONMENT Russian patent published in 2011 - IPC G09B23/28 A61K38/19 A61P43/00 

Abstract RU 2438190 C1

FIELD: medicine.

SUBSTANCE: for tissue ischemia correction, in the reduced blood circulation environment an isolated pedicle skin flap is simulated in a laboratory animal. On the first, third and fifth experimental days, recombinant erythropoietin 50 IU/kg is injected subcutaneously.

EFFECT: method provides correction of the survival rate values of ischemic tissue of an isolated skin flap with a greater area of healthy tissue in 1,5 times in comparison with control animals, including due to the effective doses developed for such experiment and regiment of the drug.

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Authors

Pokrovskij Mikhail Vladimirovich

Lazarenko Viktor Anatol'Evich

Kolesnik Inga Mikhajlovna

Pokrovskaja Tat'Jana Grigor'Evna

Danilenko Ljudmila Mikhajlovna

Novikov Oleg Olegovich

Korokin Mikhail Viktorovich

Gudyrev Oleg Sergeevich

Lopatin Dmitrij Vladimirovich

Egorova Ekaterina Olegovna

Arustamova Anna Aleksandrovna

Narykov Roman Aleksandrovich

Denisjuk Tat'Jana Alekseevna

Titareva Ljudmila Viktorovna

Sytnik Mikhail Vladimirovich

Gureev Vladimir Vladimirovich

Losenok Polina Igorevna

Sarojan Karen Vanushevich

Korolev Anton Evgen'Evich

Korokina Lilija Viktorovna

Loktionova Inna Leonidovna

Mal'Tseva Natal'Ja Viktorovna

Kuprijanova Jana Sergeevna

Dates

2011-12-27Published

2010-05-27Filed