FIELD: medicine; pharmaceuticals.
SUBSTANCE: group of inventions relates to the chemical and pharmaceutical industry and is a mixture of empty liposomes for the treatment or prevention of a bacterial infection, containing cholesterol (≥30 wt%) and sphingomyelin in a ratio of 5:1-1:2 (w/w), with other empty liposomes containing lipids or phospholipids selected from the group of cholesterol, sphingomyelins, phosphatidylcholines, phosphatidylethanolamines and phosphatidylserines, as well as to methods of treating and preventing bacterial infections using such mixtures, including when combined, parallel and mediated with standard antibiotics against bacterial infection.
EFFECT: inventions enables to prevent the death of laboratory mice infected with lethal doses of Staphylococcus aureus or Streptococcus pneumoniae.
14 cl, 1 tbl, 10 dwg, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| SPECIALLY DEVELOPED LIPOSOMES FOR TREATMENT OF BACTERIAL INFECTIONS | 2013 |
|
RU2780026C2 |
| PROLONGED RELEASE OF ANTI-INFECTIOUS AGENTS | 2006 |
|
RU2438655C2 |
| ANTIBACTERIAL AGENT FOR TREATMENT OF FARM ANIMALS AND POULTRY, METHOD OF PREVENTING AND TREATING CHICKEN SUFFERING FROM BACTERIAL- ORIGIN DISEASES, METHOD OF TREATING BACTERIAL-ORIGIN RESPIRATORY DISEASES IN CALVES, AND METHOD OF PREVENTING CATTLE TUBERCULOSIS | 1999 |
|
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| STABILISED VANCOMYCIN FORMULATIONS | 2013 |
|
RU2675859C2 |
| PREPARATION BASED ON LYTIC MYCOBACTERIOPHAGE AND A METHOD FOR PRODUCTION THEREOF | 2018 |
|
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| SMALL LIPOSOMES FOR DELIVERY OF IMMUNOGEN CODING RNA | 2011 |
|
RU2671482C2 |
| TARGET VESICULAR STRUCTURES FOR CELL PROTECTION AND FOR TREATMENT AGAINST INFECTIONS CAUSED BY HELICOBACTER PYLORI | 2000 |
|
RU2207113C2 |
| METHOD FOR TREATMENT OF BRUCELLOSIS | 2002 |
|
RU2239416C2 |
| METHOD FOR TREATMENT OF BRUCELLOSIS | 2002 |
|
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| GRANZYME B DELIVERY METHOD TO MAMMALIAN CELLS | 2021 |
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RU2796685C2 |
