FIELD: pharmaceutics.
SUBSTANCE: inventions relate to chemical-pharmaceutical industry and present a lyophilized liposome composition in gel phase for delivery of therapeutic and/or diagnostic agent, as well as a method for preparing the composition.
EFFECT: composition comprises an external cryoprotectant, with respect to said liposomes, and an internal, the concentration of which is less than 125 mM, and demonstrates excellent drug retention profiles and retains the size distribution after lyophilization and reproduction.
12 cl, 6 dwg, 6 tbl, 3 ex
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Authors
Dates
2018-03-28—Published
2012-10-15—Filed