FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to medicine, in particular, to gynecology and can be applied for treatment of precancerous diseases of uterus neck. Medicine is made in form of vaginal suppository, containing recombinant composition of proteins E7 of human papilloma virus of 16 and 18 types, bound with amino acid by sequence of heat sock protein m.m. 70 kDa from M. tuberculosis, hydrophobic base, polyethylene glycol 1500, polyethylene glycol 400, preservative, chitosan with degree of deacetylation 86%.
EFFECT: invention ensures stability of recombinant proteins, included into its composition, during long time.
1 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| MEDICINE FOR TREATMENT OF UTERUS NECK DISEASES, ASSOCIATED WITH HUMAN PAPILLOMA VIRUS, IN FORM OF VAGINAL CAPSULES | 2010 |
|
RU2438702C1 |
| DRUG FOR HUMAN PAPILLOMA VIRUS ASSOCIATED DISEASES OF UTERINE NECK, PRESENTED IN FORM OF SOLUTION FOR VAGINAL IRRIGATIONS, KIT AND METHOD FOR PREPARING | 2010 |
|
RU2438652C1 |
| VAGINAL SUPPOSITORIES FOR TREATMENT OF CERVICAL CARCINOMA | 2008 |
|
RU2404794C2 |
| MUCOSAL VACCINE FOR IMMUNE THERAPY OF DISEASES CAUSED BY HUMAN PAPILLOMA VIRUSES, AND RELATED THERAPY (VERSIONS) | 2008 |
|
RU2377305C1 |
| RECOMBINANT PROTEIN COMPOSITION, METHOD FOR PREPARING SUCH COMPOSITION, PHARMACEUTICAL KIT OF REAGENTS FOR IMMUNOTHERAPY AND PROPHYLACTIC VACCINATION OF TUMOR DISEASES IN ANUS-GENITAL SPHERE, METHOD FOR IMMUNOTHERAPY AND PROPHYLACTIC VACCINATION BASED ON THEREOF | 2002 |
|
RU2229307C1 |
| RECOMBINANT FUSED PROTEIN, PREPARATION FOR IMMUNOTHERAPY BASED ON THEREOF AND METHOD FOR IMMUNOTHERAPY OF RELAPSING LARYNX PAPILLOMATOSIS | 2005 |
|
RU2290204C1 |
| METHOD FOR TREATING INFECTION CAUSED WITH HUMAN PAPILLOMA VIRUS (HPV) | 2001 |
|
RU2282461C2 |
| METHOD FOR MICROBIOLOGICAL SYNTHESIS OF HYBRID PROTEIN E7-HSP70 (VERSIONS) | 2013 |
|
RU2546917C1 |
| METHOD FOR PRODUCTION OF PROTEIN PREPARATION BELONGING TO STRESS GENUS AND HSP70 PROTEIN PREPARATION OBTAINED BY SAID METHOD | 2005 |
|
RU2283128C1 |
| PROTEIN-PEPTIDE ANTITUMOR COMPOSITION, CELL PREPARATION ACTIVATED THEREWITH AND METHOD FOR TUMOR PROPHYLAXIS OR TREATMENT | 2004 |
|
RU2283129C1 |
