FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine and pharmaceutical industry, namely to gynaecology and can find application for treating the pre-cancer diseases of uterine neck. A drug presented in the form of a solution for vaginal irrigations, characterised by the fact that it contains a recombinant composition of proteins E7 of HPV type 16 and 18 types linked to an amino acid sequence of heat-shock proteins of m. w. 70 kDa from M. tuberculosis in the form of a lyophilised powder, chitosan of a degree of acetylation 86%, a preserving agent, carboxymethyl cellulose sodium salt of molecular weight 250000, a foaming agent selected from glycyrrhizic acid and its pharmaceutically acceptable salts, purified water. Also, there is offered a kit and method for preparing it.
EFFECT: invention provides stability of recombinant proteins in its composition throughout a long period of time.
7 cl, 1 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| MEDICINE FOR TREATMENT OF UTERUS NECK DISEASES, ASSOCIATED WITH HUMAN PAPILLOMA VIRUS, IN FORM OF VAGINAL CAPSULES | 2010 |
|
RU2438702C1 |
| MEDICATION FOR TREATMENT OF UTERUS NECK DISEASES, ASSOCIATED WITH HUMAN PAPILLOMA VIRUS, IN FORM OF VAGINAL SUPPOSITORY | 2010 |
|
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| VAGINAL SUPPOSITORIES FOR TREATMENT OF CERVICAL CARCINOMA | 2008 |
|
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|
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| MUCOSAL VACCINE FOR IMMUNE THERAPY OF DISEASES CAUSED BY HUMAN PAPILLOMA VIRUSES, AND RELATED THERAPY (VERSIONS) | 2008 |
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| IMMUNOGENIC COMPOSITION BASED ON RECOMBINANT PROTEINS E6-CBD AND E7-CBD FOR THE TREATMENT OF MALIGNANT NEOPLASMS ASSOCIATED WITH HUMAN PAPILLOMAVIRUS TYPE 16 | 2023 |
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RU2805482C1 |
