FIELD: medicine, virology.
SUBSTANCE: the present innovation deals with treating infection caused with different types of HPV. For this purpose it is necessary to introduce therapeutically efficient quantity of composition containing fusion protein that includes heat shock protein or its immunostimulating fragment and protein E7 of HPV or its antigenic fragment; or efficient quantity of the composition containing nucleic acid coding fusion protein including Hsp or its immunostimulating fragment and HPV protein or its antigenic fragment. Moreover, if the disease is caused by infection of type 1 HPV, protein E7 HPV or its antigenic fragment comes from type 2 HPV being different from type 1 HPV. The innovation enables to obtain good results due to cross reactivity at induction of immune reaction in a patient.
EFFECT: higher efficiency of therapy.
33 cl, 1 ex, 4 tbl
| Title |
Year |
Author |
Number |
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|
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|
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- Ladant Daniel
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|
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- Bkhambkhani Akkhilesh
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|
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|
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- Digtjar' Anton Vasil'Evich
- Lutsenko Elena Valer'Evna
- Lutsenko Sergej Viktorovich
- Pozdnjakova Natal'Ja Vladimirovna
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- Severin Sergej Evgen'Evich
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- Fel'Dman Natalija Borisovna
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|
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| EXPRESSING VECTOR (VARIANTS) |
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- Katrin Ju. Jansen
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|
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2002 |
- Pal'Tsev M.A.
- Severin E.S.
- Kiselev O.I.
- Kiselev V.I.
- Sveshnikov P.G.
|
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2004 |
- Kalinina Ekaterina Sergeevna
- Lutsenko Elena Valer'Evna
- Lutsenko Sergej Viktorovich
- Severin Evgenij Sergeevich
- Severin Sergej Evgen'Evich
- Fel'Dman Natalija Borisovna
- Khomjakova Anastasija Viktorovna
|
RU2283129C1 |
