FIELD: chemistry.
SUBSTANCE: invention relates to a compound of formula 
: a pharmaceutically acceptable salt or solvate thereof, having Syk kinase inhibiting properties. The invention also relates to a pharmaceutical composition containing said compound, methods of treating diseases whose development is aided by c-kit receptor activity, such as arthritis, rheumatoid arthritis, tumours, mantle cell lymphoma, as well as a method of inhibiting angiogenesis.
EFFECT: improved method.
13 cl, 4 tbl, 10 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| PYRIMIDINE INDOLE COMPOUNDS | 2010 |
|
RU2552999C2 |
| COMPOUNDS AND COMPOSITIONS AS PROTEINKINASE INHIBITORS | 2006 |
|
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| ASK1-INHIBITING PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES | 2018 |
|
RU2772422C2 |
| USE OF 2,4-DIAMINOPYRIMIDINES FOR TREATING ATHEROSCLEROSIS | 2009 |
|
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|
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| HETERODIMERIC BISPECIFIC ANTIBODY AGAINST TNFα/AGAINST IL-17A, SIMILAR BY STRUCTURE TO NATURAL ANTIBODY, AND ITS PRODUCTION METHOD | 2019 |
|
RU2781816C1 |
| METHODS OF TREATMENT OR PREVENTION OF AUTOIMMUNE DISEASES BY MEANS OF 2,4-PYRIMIDINDIAMIN COMPOUNDS | 2003 |
|
RU2376992C2 |
| 2-(3-(4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL)-1-(ETHYLSULFONYL)AZETIDIN-3-YL)ACETONITRILE HEMINAPHTHYLDISULFONATE AS JANUS KINASE INHIBITOR | 2016 |
|
RU2644155C1 |
| SOME CHEMICAL STRUCTURES, COMPOSITIONS AND METHODS | 2009 |
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| USE OF PI3K ACTIVITY OR FUNCTION INHIBITORS FOR TREATMENT OF PRIMARY SJOGREN'S SYNDROME | 2017 |
|
RU2749731C2 |
