FIELD: medicine.
SUBSTANCE: invention relates to pyrrolopyrimidine compounds according to Formula I which are ASK inhibitors, in particular ASK1 inhibitors. The present invention also relates to methods for preparing a compound of the invention, pharmaceutical compositions containing a compound of the invention for the prevention and/or treatment of pain, inflammatory conditions, cardiovascular disease, neurodegenerative disease, neurological disease, complications of type I diabetes, cancer and/or fibrotic diseases.
EFFECT: improvement of treatment of pain, inflammatory conditions, cardiovascular disease, neurodegenerative disease, neurological disease, complications of type I diabetes, cancer and/or fibrotic diseases.
11 cl, 7 dwg, 12 tbl
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