METHOD OF SELECTING TACTICS OF STARTING ANTIBACTERIAL THERAPY IN TREATMENT OF PNEUMONIA Russian patent published in 2012 - IPC A61B10/00 G01N33/48 A61K31/542 A61K31/43 A61P11/00 

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to therapy and can be used in pulmonology in selection of starting antibacterial therapy of community-acquired pneumonia (ABT CP) in patients addicted to persistent tobacco-smoking. Method includes anamnesis analysis and determination of persistent tobacco-smoking as risk factor. Additionally estimated is individual sensitivity of patient's organism to medication cefotaxime. For this purpose after introduction of cefotaxime dose to patient chromatographically determined is said medication concentration in blood serum. If concentration value is lower than 2.24 mcg/ml inhibitor-protected penicillins and other antibacterial cefotaxime-free medications are used. In tobacco-smoking patient smoking index is determined and if its value is more than 25 packets/years, in therapy inhibitor-protected penicillins and other cefotaxime-free medications are used in therapy.

EFFECT: method makes it possible to carry out adequate starting antibacterial therapy, taking into account such risk factor as tobacco-smoking, and basing on prediction of drug resistance and reduction of cefotaxime concentration in blood, which ensures increase of pneumonia treatment efficiency in said contingent of patients, reducing drug load on organism and treatment terms.

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