FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry and specifically an improved method of producing 3β, 28-hydroxylupane of formula I:
.
The method involves reduction of 3β, 28-dihydroxy-20(29)-lupene to 3β, 28-dihydroxylupane with diborane obtained in situ, with molar ratio 3β, 28-dihydroxy-20(29)-lupene:diborane equal to 1:5, in tetrahydrofuran at temperature 65°C for 4 hours.
EFFECT: output of the end product is equal to 78%.
1 cl, 1 ex
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