CYTOTOXIC AND ANTI-VIRAL ACTIVITY OF 3-ACYLOXIMETHYL-3-OXO-1-CYANO-2,3-SECO-2-NOR-TRITERPENOIDES Russian patent published in 2019 - IPC C07J41/00 C07J71/00 A61K31/56 A61K31/58 A61P31/18 A61P31/22 A61P35/00 

Abstract RU 2682669 C1

FIELD: chemistry.

SUBSTANCE: invention relates to A-secotriterpenoid 18αH-oleanic type.

.

EFFECT: new compound has been obtained that inhibits the reproduction of HIV-1 and herpes simplex viruses of type I and II and has simultaneously virucidal properties.

1 cl, 3 tbl, 5 ex

Similar patents RU2682669C1

Title Year Author Number
CYTOTOXIC AND ANTIVIRAL ACTIVITY OF 3-ACYLOXYMETHYL-3-OXO-1-CYANO-2,3-SECO-2-NOR-TRITERPENOIDS 2018
  • Krajnova Gulnaz Faizovna
  • Eroshenko Darya Vladimirovna
  • Grishko Viktoriya Viktorovna
RU2686100C1
TRITERPENE LUPANE-TYPE AMIDES WITH FRAGMENT OF 2-AMINOBUTAN-1-OL EXHIBITING VIRUS-INHIBITING AND VIRUCIDAL ACTIVITY 2017
  • Igosheva Ekaterina Viktorovna
  • Eremin Vladimir Fedorovich
  • Boreko Evgenij Ivanovich
  • Savinova Olga Vladimirovna
  • Tolmacheva Irina Anatolevna
  • Grishko Viktoriya Viktorovna
RU2664804C1
TRITERPENOIDS WITH EH-NITRILE FRAGMENT IN A-PENTACYCLE 2012
  • Grishko Viktorija Viktorovna
  • Tolmacheva Irina Anatol'Evna
  • Galajko Natal'Ja Vladimirovna
  • Boreko Evgenij Ivanovich
  • Eremin Vladimir Fedorovich
  • Savinova Ol'Ga Vladimirovna
  • Kucherov Igor' Ivanovich
RU2496785C1
A-SECO-TRITERPENOIDS WITH METHYLKETONE FRAGMENT 2013
  • Tolmacheva Irina Anatol'Evna
  • Grishko Viktorija Viktorovna
  • Pereslavtseva Anastasija Vladimirovna
  • Eremin Vladimir Fedorovich
  • Boreko Evgenij Ivanovich
  • Kucherov Igor' Ivanovich
  • Savinova Ol'Ga Vladimirovna
RU2537840C1
METHYL ESTERS 3-METHYL-3-OXO-1-CYANO-2,3-SECO-2-NORLUP-20(29)-ENE-30-AL-28 AND 3-BROMETHYLENE-3-OXO-1-CYANO -2,3-SECO-2-NORLUP-20(29)-ENE-30-AL-28 ACIDS WHICH EXHIBIT CYTOTOXIC ACTIVITY 2016
  • Konysheva Anastasiya Vladimirovna
  • Nebogatikov Vladimir Olegovich
  • Tolmacheva Irina Anatolevna
  • Grishko Viktoriya Viktorovna
  • Rybalkina Ekaterina Yurevna
  • Karamysheva Aida Fuadovna
RU2632002C1
24-DIBROM-4-OXO-2-CYANO-3,23-DINOLUP-28-OIC ACID METHYL ETER WITH CYTOTOXIC ACTIVITY 2022
  • Tolmacheva Irina Anatolevna
  • Nazarov Mikhail Andreevich
  • Gagarskikh Olga Nikolaevna
  • Grishko Viktoriya Viktorovna
RU2784317C1
LUPANE A-SECO-TRITERPENOIDS EXHIBITING ANTIVIRAL ACTIVITY 2011
  • Tolmacheva Irina Anatol'Evna
  • Grishko Viktorija Viktorovna
  • Igosheva Ekaterina Viktorovna
  • Boreko Evgenij Ivanovich
  • Eremin Vladimir Fedorovich
  • Kucherov Igor' Ivanovich
  • Savinova Ol'Ga Vladimirovna
RU2470003C1
2,3-SECO-DERIVATIVES OF BETULONIC ACID 2009
  • Tolmacheva Irina Anatol'Evna
  • Grishko Viktorija Viktorovna
  • Boreko Evgenij Ivanovich
  • Savinova Ol'Ga Vladimirovna
  • Pavlova Natal'Ja Il'Inichna
RU2410390C1
3-HYDROXIMINO DERIVATIVES OF 2,3-SECOLUPANE TYPE, DEMONSTRATING INHIBITING ACTIVITY WITH RESPECT TO INFLUENZA A AND HIV-1 VIRUS 2011
  • Grishko Viktorija Viktorovna
  • Tolmacheva Irina Anatol'Evna
  • Galajko Natal'Ja Vladimirovna
  • Boreko Evgenij Ivanovich
  • Eremin Vladimir Fedorovich
  • Savinova Ol'Ga Vladimirovna
  • Kucherov Igor' Ivanovich
RU2475476C1
HIV-1 AND INFLUENZA A VIRUS REPRODUCTION INHIBITOR 2012
  • Boreko Evgenij Ivanovich
  • Eremin Vladimir Fedorovich
  • Grishko Viktorija Viktorovna
  • Tolmacheva Irina Anatol'Evna
RU2477134C1

RU 2 682 669 C1

Authors

Krajnova Gulnaz Faizovna

Savinova Olga Vladimirovna

Eroshenko Darya Vladimirovna

Boreko Evgenij Ivanovich

Eremin Vladimir Fedorovich

Grishko Viktoriya Viktorovna

Dates

2019-03-20Published

2018-07-09Filed