FIELD: chemistry.
SUBSTANCE: invention relates to the field of chemistry of natural compounds of the class of 3,4-secolupane triterpenoids - methyl ester of 24,24-dibromo-4-oxo-2-cyano-3,23-dinorlupan-28-oic acid, which exhibits cytotoxic activity, in including cancer cell lines MCF-7, HCT 116, RD TE 32, MS, A549, PC-3, HepG2, HBL-100, HBL-100/Dox.
EFFECT: providing 3,4-seco-lupane triterpenoids, which contain dibromo and nitrile groups in the cleaved A ring and have cytotoxic properties.
2 cl, 2 tbl, 2 ex
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Authors
Dates
2022-11-23—Published
2022-06-06—Filed