CYTOTOXIC AND ANTIVIRAL ACTIVITY OF 3-ACYLOXYMETHYL-3-OXO-1-CYANO-2,3-SECO-2-NOR-TRITERPENOIDS Russian patent published in 2019 - IPC C07J41/00 A61K31/56 A61P35/00 

Abstract RU 2686100 C1

FIELD: chemistry.

SUBSTANCE: invention relates to A-seco-tritrnerophenoids of general formula I.

.

EFFECT: obtaining novel A-secotreterpenoids exhibiting cytotoxic activity on tumor cells of lines NST 116 (colorectal carcinoma), MS (melanoma), RD TE32 (rhabdomyosarcoma).

3 cl, 3 tbl, 5 ex

Similar patents RU2686100C1

Title Year Author Number
CYTOTOXIC AND ANTI-VIRAL ACTIVITY OF 3-ACYLOXIMETHYL-3-OXO-1-CYANO-2,3-SECO-2-NOR-TRITERPENOIDES 2018
  • Krajnova Gulnaz Faizovna
  • Savinova Olga Vladimirovna
  • Eroshenko Darya Vladimirovna
  • Boreko Evgenij Ivanovich
  • Eremin Vladimir Fedorovich
  • Grishko Viktoriya Viktorovna
RU2682669C1
METHYL ESTERS 3-METHYL-3-OXO-1-CYANO-2,3-SECO-2-NORLUP-20(29)-ENE-30-AL-28 AND 3-BROMETHYLENE-3-OXO-1-CYANO -2,3-SECO-2-NORLUP-20(29)-ENE-30-AL-28 ACIDS WHICH EXHIBIT CYTOTOXIC ACTIVITY 2016
  • Konysheva Anastasiya Vladimirovna
  • Nebogatikov Vladimir Olegovich
  • Tolmacheva Irina Anatolevna
  • Grishko Viktoriya Viktorovna
  • Rybalkina Ekaterina Yurevna
  • Karamysheva Aida Fuadovna
RU2632002C1
TRITERPENE LUPANE-TYPE AMIDES WITH FRAGMENT OF 2-AMINOBUTAN-1-OL EXHIBITING VIRUS-INHIBITING AND VIRUCIDAL ACTIVITY 2017
  • Igosheva Ekaterina Viktorovna
  • Eremin Vladimir Fedorovich
  • Boreko Evgenij Ivanovich
  • Savinova Olga Vladimirovna
  • Tolmacheva Irina Anatolevna
  • Grishko Viktoriya Viktorovna
RU2664804C1
24-DIBROM-4-OXO-2-CYANO-3,23-DINOLUP-28-OIC ACID METHYL ETER WITH CYTOTOXIC ACTIVITY 2022
  • Tolmacheva Irina Anatolevna
  • Nazarov Mikhail Andreevich
  • Gagarskikh Olga Nikolaevna
  • Grishko Viktoriya Viktorovna
RU2784317C1
A-SECO-TRITERPENOIDS WITH METHYLKETONE FRAGMENT 2013
  • Tolmacheva Irina Anatol'Evna
  • Grishko Viktorija Viktorovna
  • Pereslavtseva Anastasija Vladimirovna
  • Eremin Vladimir Fedorovich
  • Boreko Evgenij Ivanovich
  • Kucherov Igor' Ivanovich
  • Savinova Ol'Ga Vladimirovna
RU2537840C1
TRITERPENOIDS WITH EH-NITRILE FRAGMENT IN A-PENTACYCLE 2012
  • Grishko Viktorija Viktorovna
  • Tolmacheva Irina Anatol'Evna
  • Galajko Natal'Ja Vladimirovna
  • Boreko Evgenij Ivanovich
  • Eremin Vladimir Fedorovich
  • Savinova Ol'Ga Vladimirovna
  • Kucherov Igor' Ivanovich
RU2496785C1
LUPANE A-SECO-TRITERPENOIDS EXHIBITING ANTIVIRAL ACTIVITY 2011
  • Tolmacheva Irina Anatol'Evna
  • Grishko Viktorija Viktorovna
  • Igosheva Ekaterina Viktorovna
  • Boreko Evgenij Ivanovich
  • Eremin Vladimir Fedorovich
  • Kucherov Igor' Ivanovich
  • Savinova Ol'Ga Vladimirovna
RU2470003C1
2,3-SECO-DERIVATIVES OF BETULONIC ACID 2009
  • Tolmacheva Irina Anatol'Evna
  • Grishko Viktorija Viktorovna
  • Boreko Evgenij Ivanovich
  • Savinova Ol'Ga Vladimirovna
  • Pavlova Natal'Ja Il'Inichna
RU2410390C1
ACETYLHYDRAZONE 1-CYANO-19β,28-EPOXY-2,3-SECO-18α-OLEAN-3-AL, EXHIBITING INHIBITING ACTIVITY TOWARDS VESICULAR STOMATITIS VIRUS "INDIANA" STRAIN 2010
  • Grishko Viktorija Viktorovna
  • Tolmacheva Irina Anatol'Evna
  • Galajko Natal'Ja Vladimirovna
  • Strel'Nikov Vladimir Nikolaevich
  • Volkova Larisa Vladimirovna
  • Perevozchikova Elena Nikolaevna
  • Pestereva Svetlana Aleksandrovna
  • Kaz'Janin Aleksandr Viktorovich
RU2429227C1
3-HYDROXIMINO DERIVATIVES OF 2,3-SECOLUPANE TYPE, DEMONSTRATING INHIBITING ACTIVITY WITH RESPECT TO INFLUENZA A AND HIV-1 VIRUS 2011
  • Grishko Viktorija Viktorovna
  • Tolmacheva Irina Anatol'Evna
  • Galajko Natal'Ja Vladimirovna
  • Boreko Evgenij Ivanovich
  • Eremin Vladimir Fedorovich
  • Savinova Ol'Ga Vladimirovna
  • Kucherov Igor' Ivanovich
RU2475476C1

RU 2 686 100 C1

Authors

Krajnova Gulnaz Faizovna

Eroshenko Darya Vladimirovna

Grishko Viktoriya Viktorovna

Dates

2019-04-24Published

2018-12-20Filed