CARNIVORE CUTANEOUS CANDIDIASIS ASSOCIATED VACCINE, METHOD FOR PREPARING CARNIVORE CUTANEOUS CANDIDIASIS ASSOCIATED VACCINE, METHOD FOR PREVENTING AND TREATING CARNIVORE CUTANEOUS CANDIDIASIS Russian patent published in 2012 - IPC A61K36/62 A61K47/02 C12N1/14 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to veterinary mycology, and concerns preparing a carnivore cutaneous candidiasis vaccine. As antigens the offered associated carnivore cutaneous candidiasis vaccine contains blastospores of immune strains C. albicans No.95 and C. tropicalis No.87 taken in equal proportions (1:1) with a final amount of 10-40 mil. blastospores per 1 cm³ of 0.8-1% sodium thiosulphate. A method for making such vaccine involves separate homogenisation of a biomass of mycotic blastospores in the sodium thiosulphate solution, measurement of the blastospore content, standartisation of the homogenates to the concentration of 10-40 min. blastospores in 1 cm³ by sparing sterilisation by intermittent steaming and mixing of the prepared homogenates. A method for preventing and treating of carnivore cutaneous candidiasis consists in intramuscular introduction of the vaccine at first in one point, and then in 12-16 days in the opposite point in therapeutic doses.

EFFECT: invention enables creating a high-level lasting immunity in carnivores.

3 cl, 2 tbl