ELIMINATION OF INVOLVEMENT OF CONTRAST AGENT CONCENTRATION IN MRT Russian patent published in 2012 - IPC A61K49/06 A61B6/06 

FIELD: medicine.

SUBSTANCE: invention refers to a method for obtaining the information describing a physical-chemical parameter by the magnetic-resonant tomography (MRT) after a contrast medium is introduced to a patient. Said contrast medium contains a resistant contrast-increasing component giving a first signal with a contrast-increasing ability which is independent of the physical-chemical parameter to be determined, and an unaffected contrast-increasing component giving a second signal different from the first one with the contrast-increasing ability which depends on the physical-chemical parameter to be determined. The declared method involves MRT imaging of a patient's body, calibration imaging by recording of the first signal from the resistant contrast-increasing component, and measuring of the physical-chemical parameter by the MRT images and the calibration images with the calibration images being used in order to adjust the physical-chemical parameter to calculate the involvement of the contrast agent concentration in the MRT imaging. Besides, the invention refers to a data medium which stores a machine readable software wherein the method stated above is implemented on a computer. The invention also refers to a MRT system comprising a MRT imaging means, a calibration imaging means, and a means for measuring the physical-chemical parameter, as well as to an intravenous preparation containing the contrast agent specified above.

EFFECT: invention provides the decreased or eliminated involvement of the contrast agent involvement in the MRT imaging.

29 cl, 3 dwg