FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to a carrier applicable for the local drug delivery. A drug is enclosed in a carrier, and the carrier comprises a coating able to release an enclosed drug as a result of a local stimulus. The coating additionally surrounds the contrast agent MR 19F which changes its detectability after being released from the carrier. The invention refers to a method for the drug delivery to an MRT-controlled individual, wherein the method involves administering the above carrier into the individual enabling the carrier releasing the drug, and forming MR 19F images with the use of a contrast produced by the contrast agent MR 19F.
EFFECT: invention enables monitoring the beginning of the drug release from the carrier.
18 cl, 11 dwg, 2 tbl, 2 ex
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Authors
Dates
2014-09-10—Published
2009-09-03—Filed