FIELD: medicine.
SUBSTANCE: kit contains a component that is a meningococcal saccharide conjugate, a pneumococcal saccharide conjugate component, and an additional immunogenic component for administration to different sites at substantially the same time. Where: (a) the meningococcal saccharide conjugate component contains at least a capsular saccharide Neisseria meningitidis of serogroup C conjugated to the first carrier protein, but does not contain an aluminium phosphate adjuvant; (b) the pneumococcal saccharide conjugate component comprises at least one capsular saccharide of Streptococcus pneumoniae conjugated to the second carrier protein; and (c) the additional immunogenic component comprises the cell-free antigen(s) B. pertussis and an inactivated poliovirus antigen (IPV), and one or more antigens selected from diphtheria toxoid, tetanus toxoid, HBsAg and conjugated Hib saccharide, the carrier protein of at least one meningococcal saccharide conjugate and the carrier protein of at least one pneumococcal saccharide conjugate are the same.
EFFECT: use of this kit allows safe introduction of conjugates of the meningococcal saccharide and conjugates of the pneumococcal saccharide simultaneously, but separately, with an additional component containing acellular antigens and inactivated poliovirus antigen.
15 cl
