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(19)

(11)

2 449 990

(13)

(51)

IPC

C07D209/14(2006-01-01)

C07D401/06(2006-01-01)

C07D401/12(2006-01-01)

C07D403/06(2006-01-01)

C07D409/12(2006-01-01)

C07D513/04(2006-01-01)

A61K31/404(2006-01-01)

(21) (22)

Application

2009103313/04, 2007-07-03

(24)

Start date

2007-07-03

(22)

Actual filing date

2007-07-03

(45)

Published

2012-05-10

(72)

Inventor

Jokhansson GariAngbrant JokhanRingom RuneBejerlejn KatarinaKhammer KristinRingberg EhrikLindkvist BengtBrandt PeterNil'Sson B'Ern M.

(73)

Holder

Biovitrum Ab

INDOLES AS 5-HT MODULATORS Russian patent published in 2012 - IPC C07D209/14 C07D401/06 C07D401/12 C07D403/06 C07D409/12 C07D513/04 A61K31/404

Abstract RU 2449990 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to new compounds of formula

wherein: m, n, R⁰, R¹, R², R³ and R⁴ have the values presented in clause 1 of the patent claim provided the compound of formula (I) cannot represent N-methyl-1-(phenylsulphonyl)-1H-indole-4-methanamine.

EFFECT: compounds show 5-NT₆ receptor antagonist activity that that allows them being used in the pharmaceutical composition.

19 cl, 3 tbl, 192 ex

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RU 2 449 990 C2

Authors

Jokhansson Gari

Angbrant Jokhan

Ringom Rune

Bejerlejn Katarina

Khammer Kristin

Ringberg Ehrik

Lindkvist Bengt

Brandt Peter

Nil'Sson B'Ern M.

Dates

2012-05-10—Published

2007-07-03—Filed