FIELD: medicine.
SUBSTANCE: present invention relates to novel conjugates of binding compound – active compound of (ADC) N,N-alkylauristatins targeted against target C4.4a, active metabolites of said ADC conjugates, method of obtaining said ADC conjugates, use of said ADC conjugates for treating and/or preventing diseases, as well as use of these ADC conjugates to produce medicinal agents for treating and/or preventing diseases, more specifically hyperproliferative and/or angiogenic diseases, such as, for example, cancer.
EFFECT: such drug treatment can be used in form of single agent therapy or, in another version, in combination with other drugs or additional other therapeutic measures.
52 cl, 6 tbl, 128 ex
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