IpaD-PROTEIN SHIGELLA AND APPLYING IT AS SHIGELLA INFECTIONS VACCINE Russian patent published in 2012 - IPC A61K39/112 C07K14/25 A61K39/395 A61P31/04 

Abstract RU 2450826 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to medicine and concerns IpaD-protein Shigella and applying it as a Shigella infections vaccine. Substance of the inventions involves compositions and methods of blocking of bacteria Shigella penetration in mammal cells and providing protection against the infections caused by bacteria Shigella, or reducing a severity of Shigella infections, including polypeptide IpaD able to form neutralised antibodies showing protective action against some serotypes of bacteria Shigella, particularly S.flexneri.

EFFECT: creation of the compositions and the methods for applying them, effective for Shigella caused dysentery.

22 cl, 4 ex, 7 dwg

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RU 2 450 826 C2

Authors

Alaui Adbel'Munaehm

Sansonetti Filippe

Sani Musa

Boto Anna

Parso Klod

Boekema Ehgbert Dzh.

Dates

2012-05-20Published

2007-10-12Filed