FIELD: medicine, pharmaceutics.
SUBSTANCE: described is a new polycyclic compound with general formula 
(I-1) and 
(1-3) or a pharmaceutically acceptable salt thereof where X1- -CR1 =CR2 - where R1 and R2 independently stand for hydrogen or C1-6 alkyl while Het stands for a radical of the following formulae: 
that may be substituted 1-3 times additionally described is a pharmaceutical composition containing such compound and intended for prevention or treatment of diseases caused by β-amyloid.
EFFECT: production of a pharmaceutical composition prevention or treatment of diseases caused by β-amyloid.
7 cl, 392 ex, 12 tbl
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