FIELD: medicine.
SUBSTANCE: declared invention refers to chemical-pharmaceutical industry, and concerns a method for making dry powder glycopyrronium salt inhalation compositions characterised by high stability. The method involves (a) finish grinding of glycopyrronium salt together with an anti-adhesive agent and (b) mixing with carrier particles with making a dry powder composition where the carrier particles are mixed with the fine mixture of glycopyrronium salt and the anti-adhesive agent at the mass ratio varying within 200:1 to 20:1.
EFFECT: prepared inhalation compositions possess high storage stability.
13 cl, 2 ex, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PRODUCING CARRIER PARTICLES FOR DRY POWDERS FOR INHALATIONS | 2011 |
|
RU2585101C2 |
| PHARMACEUTIC COMPOSITIONS | 2005 |
|
RU2396943C2 |
| NOVEL CARRIER PARTICLES FOR DRY POWDER INHALATION FORMULATIONS | 2020 |
|
RU2823554C1 |
| ORGANIC COMPOUNDS | 2008 |
|
RU2482838C2 |
| METHOD FOR PRODUCING LOW-STATIC PARTICLES | 2011 |
|
RU2580312C2 |
| ORGANIC COMPOUNDS | 2008 |
|
RU2496479C2 |
| PHARMACEUTICAL DRUG FORMS CONTAINING LOW-DOSAGE ACTIVE COMPONENT FOR DRY POWDER INHALATORS | 2005 |
|
RU2371171C2 |
| OBTAINING MICRONIZED GLYCOPYRRONIUM SALT PARTICLES BY HYDRODYNAMIC CAVITATION | 2017 |
|
RU2723549C2 |
| METHOD OF PRODUCING PYRROLIDINIUM SALTS | 2010 |
|
RU2554878C2 |
| METHOD OF PRODUCING A DRY POWDER COMPOSITION CONTAINING AN ANTICHOLINERGIC, CORTICOSTEROID AND BETA-ADRENERGIC AGENT | 2018 |
|
RU2741427C1 |
