FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to a method for preparing an inhaled fine or crystalline glycopyrronium powder salt. The declared method involves suspending the crystalline glycopyrronium salt in acetone to prepare a suspension, homogenising the suspension at pressure 500-2000 bar to prepare glycopyrronium salt particles at average particle size less than 10 mcm, and drying the glycopyrronium salt particles to remove residual acetone if any.
EFFECT: invention provides preparing the aggregation and agglomeration resistant crystalline glycopyrronium powder salt.
7 cl, 2 tbl, 4 ex
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Authors
Dates
2013-10-27—Published
2008-12-11—Filed