FIELD: chemistry.
SUBSTANCE: invention relates to humanised anti-beta 7 antibodies; a composition containing said antibody; a method of inhibiting interaction of human integrin beta 7 subunits with a second integrin subunit using said antibody; as well as a version of use of the listed antibodies.
EFFECT: invention can be used to treat chronic inflammatory diseases such as asthma, Crohn's disease, ulcerative colitis, diabetes, complications during organ transplantation and diseases associated with allotransplantation.
47 cl, 22 dwg, 10 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHODS OF ADMINISTERING INTEGRIN BETA7 ANTAGONISTS | 2012 |
|
RU2595836C2 |
| THEOPHYLLINE ANTIBODIES AND METHODS FOR THEIR APPLICATION | 2013 |
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| HUMANISED ANTI c-met ANTAGONISTS | 2005 |
|
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| HUMANISED ANTI-FACTOR D ANTIBODIES AND APPLICATIONS THEREOF | 2012 |
|
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| HUMANISED ANTI-FACTOR D ANTIBODIES AND USE THEREOF | 2007 |
|
RU2474589C2 |
| ANTIBODIES AGAINST 5-BROMO-2'-DEOXYURIDINE AND METHODS OF USE | 2015 |
|
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| ANTIBODIES TO BIOTIN AND APPLICATION METHODS | 2013 |
|
RU2630296C2 |
| MONOVALENT CARRIER MODULES ACROSS BLOOD-BRAIN BARRIER | 2014 |
|
RU2694659C2 |
| UNIVERSAL TRANSMITTER MODULES THROUGH THE HEMATOENCEPHALITIC BARRIER | 2014 |
|
RU2799436C1 |
| ANTI-CD79b ANTIBODIES AND IMMUNOCONJUGATES AND METHODS FOR USING THEM | 2009 |
|
RU2553566C2 |
