PASSAGE VECTOR AND VACCINE FOR TUBERCULOSIS Russian patent published in 2012 - IPC C12N15/63 A61K39/04 

FIELD: medicine.

SUBSTANCE: passage vector contains fused DNA under control of a fused promoter. Fused DNA consists of a DNA fragment coding protein antigen M. tuberculosis, and a gene DNA fragment coding an amino acid sequence under accession number GenBank No.L22858. The double promoter consists of a polyhedrin promoter and a CMV promoter. What is also described is a vaccine for tuberculosis containing a recombinant nuclear polyhedrosis virus Autographa californica (AcNPV) as an active agent. The recombinant AcNPV contains a sequence coming into the vector described above.

EFFECT: more effective use in medicine.

6 cl, 15 dwg, 1 tbl, 13 ex