MULTIVALENT INFLUENZA VACCINE Russian patent published in 2019 - IPC C12N7/00 C12N15/63 C12N5/02 A61K39/00 

FIELD: biotechnologies.

SUBSTANCE: invention relates to the biotechnology. Described is a polyvalent influenza vaccine containing HPV, where haemagglutinin, neuraminidase and M1 protein genes are obtained from strain A/California/04/2009; haemagglutinin gene is obtained from strain A/Michigan/45/2015, and neuraminidase and M1 protein genes are obtained from strain A/California/04/2009; haemagglutinin gene is obtained from strain A/Novosibirsk/01/2014, and neuraminidase and M1 protein genes are obtained from strain A/California/04/2009; haemagglutinin gene is obtained from strain A/HongKong/4801/2014, and neuraminidase and M1 protein genes are obtained from strain A/California/04/2009; haemagglutinin gene is obtained from strain B/Phuket/3073/13, and neuraminidase and M1 protein genes are obtained from strain A/California/04/2009 or haemagglutinin gene is obtained from strain B/Brisbane/60/2008, and neuraminidase and M1 protein genes are obtained from strain A/California/04/2009.

EFFECT: invention enables to obtain HPV influenza virus having high haemagglutination activity.

1 cl, 44 dwg, 15 tbl, 7 ex