FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutics and medicine and concerns triindolyl methane derivatives of formula
and as anticancer drugs showing cytotoxic, apoptotic action on tumour cells, and also blocking NFkB transcription factor activity.
EFFECT: compounds exhibit high anticancer activity.
4 dwg, 3 tbl, 4 ex
Title | Year | Author | Number |
---|---|---|---|
PHARMACEUTICAL COMPOSITION BASED ON TRIINDOLYLMETHANE DERIVATIVE AS ANTI-TUMOUR MEDICATION | 2012 |
|
RU2549430C2 |
INDOLOCARBAZOLE DERIVATIVE BLOCKING TUMOUR VASCULOGENIC MIMICRY | 2014 |
|
RU2557554C1 |
DERIVATIVES OF OLIVOMYCIN 1, ANTIBIOTIC OF AUREOLIC ACID GROUP WITH ANTICANCER ACTIVITY, AND METHOD OF PRODUCTION THEREOF | 2007 |
|
RU2350621C1 |
N-GLYCOSIDES OF INDOLO[2,3-a]PYRROLO[3,4-c]CARBAZOLES HAVING ANTITUMOUR ACTIVITY | 2014 |
|
RU2548045C1 |
ANTITUMOUR ANTHRAFURANDIONE AND BASED PHARMACEUTICAL COMPOSITIONS | 2014 |
|
RU2554939C1 |
MULTITARGET INHIBITORS OF TUMOUR GROWTH BASED ON LINEAR HETEROARENE ANTHRACENEDIONES | 2013 |
|
RU2527273C1 |
SEMI-SYNTHETIC ANALOGUES OF AUREOLIC ACID OLIVOMYCIN A ANTIBIOTIC, HAVING ANTI-TUMOUR ACTIVITY, AND SYNTHESIS METHOD THEREOF | 2010 |
|
RU2453552C2 |
N-[3-OXOLUP-20(29)-ENE-28-OIL]-2,2,6,6-TETRAMETHYLPIPERIDINE-4-YLAMINE WITH CYTOTOXIC ACTIVITY IN RESPECT OF HUMAN TUMOUR CELLS | 2017 |
|
RU2641900C1 |
HUMAN T-LYMPHOBLASTIC LEUCEMIA A4 CELL LINE USEFUL IN SCREENING OF ANTITUMOR AGENTS | 2004 |
|
RU2267532C1 |
ANTITUMOUR AGENT | 2014 |
|
RU2572691C1 |
Authors
Dates
2012-06-27—Published
2010-09-16—Filed