FIELD: biotechnology.
SUBSTANCE: invention relates to novel indolopyrrolocarbazole derivatives, which can be used for treating tumours, having the general formula I 
, where Gly is pentose residues (L-arabinose, D-ribose, D-xylose) and hexose (D-galactose), R is an amino-group, benzamide-group, (pyridin-2-yl) amino-group, acetamide-group or urea-group.
EFFECT: new compounds are proposed, having the pronounced cytotoxic activity.
4 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| DERIVATIVE OF THE CLASS OF N-GLYCOSIDES INDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE-5,7-DIONE - N-{12-(β-D-XYLOPYRANOSYL)-5,7-DIOXO-INDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOL-6-YL} PYRIDINE-2-CARBOXAMIDE, WHICH HAS CYTOTOXIC AND ANTITUMOR ACTIVITY | 2017 |
|
RU2667906C1 |
| METHOD OF PRODUCING INDOLO[2,3]PYRROLO[3,4-c]CARBAZOLE-5,7-DIONES N-GLYCOSIDES EXHIBITING CYTOTOXIC AND ANTICANCER ACTIVITY | 2009 |
|
RU2427585C9 |
| ANTITUMOUR AGENT | 2014 |
|
RU2572691C1 |
| INDOLOCARBAZOLE DERIVATIVE BLOCKING TUMOUR VASCULOGENIC MIMICRY | 2014 |
|
RU2557554C1 |
| TUMOUR THERAPY AGENT | 2019 |
|
RU2726801C1 |
| METHOD FOR PRODUCING AMINO ACID ANALOGUES OF THE ANTITUMOUR ANTIBIOTIC REBECCAMYCIN | 2020 |
|
RU2755572C1 |
| METHOD FOR TREATMENT OF SW620 HUMAN COLON CANCER IN EXPERIMENT | 2017 |
|
RU2665168C1 |
| DERIVATIVES OF GLYCOSIDES OF INDOLO[2,3-A]-PYRROLO[3,4-C]CARBAZOL-5,7-DIONES ELICITING CYTOTOXIC AND ANTITUMOR ACTIVITY | 2003 |
|
RU2255089C1 |
| ANTI-CANCER DRUG TOPOISOMERASE I INHIBITOR | 2022 |
|
RU2786727C1 |
| INDOLOPYRROLOCARBAZOLE DERIVATIVES OF SUGARS, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF AND METHOD OF INHIBITION OF TUMOR PROLIFERATION | 1997 |
|
RU2167880C2 |
