FIELD: medicine.
SUBSTANCE: invention refers to medicine, more specifically to haematology, and is applicable for immune response modulation, particularly for prevention of acute graft-versus-host disease following marrow allografting. Donor multipotent mesenchymal stromal cells recovered from bone marrow, cultured on a human blood plasma medium enriched in platelet lysate are introduced intravenously in the amount of 1x106 grafted cells per one kg of patient's body weight at the moment of leukocyte recovery in patient's peripheral blood following marrow allografting min. 1.0×109/l.
EFFECT: method provides effective prevention of acute graft-versus-host disease following marrow allografting.
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Authors
Dates
2012-06-27—Published
2010-12-14—Filed