FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions relates to medicine and deals with compound which contains a) first component, able to bind with receptors of cells ER+ and b) second component, where first component is selective modulator of estrogen receptor (SERM), and where second component represents toxin, inactivating ribosomes, and is conjugated with first component, as well as deals with pharmaceutical composition, compound application, method of obtaining and method of cancer treatment.
EFFECT: group of invention ensures reduction of tumour without toxic side effects of medication action.
28 cl, 6 ex, 5 dwg
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Authors
Dates
2012-07-20—Published
2008-09-11—Filed